C.WANG

Jackie is now a full professor at China Agriculture University in Beijing, China.

(Click for a link to her page)

Yuanyuan is now a senior scientist at Eurofin.

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Jie is now an assistant professor at University of Michigan at Dearborn.

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Sherry is currently a postdoc at Harvard University.

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Zhenming (Jimmy) is now the manager of NMR center at Georgia State University.

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Yangzhong is now a professor at the University of Science and Technology of China.

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Shannon sucessfully completed his defense and has taken a full time position.

Anqesha sucessfully completed his defense and has taken a full time position.

Dylan sucessfully completed his defense and has taken a full time position.

Nicolina carried out high presssure NMR studies of Aβ mutants (published in Chemical Communications in 2018) and s tudied a key topic in the generation of Aβ: how substrate APPTM interacts intramembrane protease. Her publication in Scientific Reports in 2018 represents the first study of substrate-intramembrane protease interaction at atomic resolution, with important implications for many diseases, such as Alzheimer’s and cancer. She is currently a postdoctoral scientist at Van Andel Research Institute, carrying out cryoEM studies of membrane proteins.

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Jian Xie studied the relationship between Zinc and Hedgehog signaling and discovered that Zn diffciency may be related to Hedgehog activation in cancers. This work was published in JBC and was one of most viewed papers on JBC website. Jian then went on to study the mechanism of a special process in Hedgehog signaling, called Hedgehog autoprocessing and described a new structural mechanism in a publication in JACS. He is now a postdoctoral research associate at Yale University.

David was a joint student between Angel Garcia and me. He carried out combined NMR and MD studies of Aβ, which provided unprecedented insight into the structure and dynamics of Aβ. He has published a number of high impact papers. For example, his 2013 JMB paper (Rosenman, David J., et al. "Aβ monomers transiently sample oligomer and fibril-like configurations: ensemble characterization using a combined MD/NMR approach." Journal of molecular biology 425.18 (2013): 3338-3359.) has already been cited over 120 times! He is currently a Protein Characterization Scientist at Eurofins

Chris carried out NMR drug screening for Aβ, and he found that tranilast, an approved drug in Asia, can bind to Aβ and promote Aβ fibrillation. This is one of the early examples of drug discovery in intrinsically disordered protein (IDP) using a combined MD/NMR approach! He is currently a Senior Scientist at Xtal BioStructures Inc.

Wen Chen solved the NMR structure of APPTM, an important domain in the generation of Aβ, resulting in a paper in Nature Communications. This work establishes a new structural mechanism for several genetic variants of Alzheimer’s disease (AD) and has been widely cited, e.g., by the premium AD research website alzforum. He also was the first to discover the intramolecular disulfide bond at intein active site, an excellent study published in Journal of American Chemical Society. He is currently a research associate at Harvard Medical School.

Jiajing solved two NMR structures. We shared a strong interest in human health and diseases. After RPI, he went on to obtain an MD at Tufts Medical School and is now practising medicine in Worcester, MA.

Yilin was Dr. Wang's first graduate student and he carried out detailed NMR studies of amyloid β-peptide, a key molecule in Alzheimer’s disease. His first paper on the dynamics of Aβ, also the first paper of my lab, has been cited over 200 times now. He obtained his PhD in four years, with a total of 8 publications, including papers in Nature Medicine, Journal of American Chemical Society. He is currently Head of Protein Science in the newly established Pfizer Asia Discovery Labs in Shanghai.

Nabin has moved on to Regeneron.